Skip to main content

Intensive Care

Our team investigates fundamental mechanisms and translates findings from bench to bedside, combining preclinical models with clinical insight.

Researcher at ICRC with focus on translational medicine. Combines preclinical insights with clinical practice across cardiology, neurology, and oncology programs.

Currently leads / contributes to interdisciplinary projects bridging molecular biology, imaging, and patient care at St. Anne's University Hospital Brno.

Research Group

Team size
Team size: 2 Researchers
Place
Place: Building A1, 3rd Floor
Collaborates with
Collaborates with Mayo Clinic, USA

Head of Research Group

doc. MUDr. Pavel Suk, Ph.D.
doc. MUDr. Pavel Suk, Ph.D.
doc. MUDr. Pavel Suk, Ph.D.

Team Assistant

Main Objectives

  1. improvement of outcomes of high-risk surgical patients
  2. deeper understanding of sepsis with a potential to improve diagnosis (new biomarkers) and treatment
  3. pharmacotherapy optimization in critically ill patients

Research focus

ventilatory efficiency and prehabilitation in high-risk patients undergoing pulmonary resection

oxidative stress in patients undegoing vascular surgery

biomarkers of sepsis/septic shock

pharmacokinetics in critically ill patients with organ dysfunction or extracorporeal circuit

Technological equipment

  • Extracorporeal Membrane Oxygenation

Selected Results

  • Brat K, Chobola M, Homolka P, Heroutova M, Benej M, Mitas L, Olson LJ, Cundrle I. Poor ventilatory efficiency during exercise may predict prolonged air leak after pulmonary lobectomy. Interact Cardiovasc Thorac Surg. 2020 01;30(2):269–72.
  • Suk P, Šrámek V, Cundrle I. Extracorporeal Membrane Oxygenation Use in Thoracic Surgery. Membranes. 2021 Jun;11(6):416.
  • Brat K, Homolka P, Merta Z, Chobola M, Heroutova M, Bratova M, Mitas L, Chovanec Z, Horvath T, Benej M, Ivicic J, Svoboda M, Sramek V, Olson LJ, Cundrle I Jr. Prediction of Postoperative Complications: Ventilatory Efficiency and Rest End-tidal Carbon Dioxide. Ann Thorac Surg. 2022 Jan 21:S0003-4975(22)00060-1.
  • Helan M, Malaska J, Tomandl J, Jarkovsky J, Helanova K, Benesova K, Sitina M, Dastych M, Ondrus T, Pavkova Goldbergova M, Gal R, Lokaj P, Tomandlova M, Parenica J. Kinetics of Biomarkers of Oxidative Stress in Septic Shock: A Pilot Study. Antioxidants (Basel). 2022 Mar 26;11(4):640.
  • Suk P, Rychlíčková J. Pharmacokinetics of colistin during extracorporeal membrane oxygenation. J Antimicrob Chemother. 2022 May 24:dkac163.